Phenazopyridine-induced hepatitis.

Phenazopyridine-induced hemolytic anemia in a patient with G6PD deficiency.

Bioassay of phenazopyridine hydrochloride for possible carcinogenicity.

A bioassay of phenazopyridine hydrochloride for possible carcinogenicity was conducted by administering the test chemical in feed to Fischer 344 rats and B6C3F1 mice. Groups of 35 rats and 35 mice of each sex were administered phenazopyridine hydrochloride at one of the following doses, either 3,700 or 7,500 ppm for rats and either 600 or 1,200 ppm for mice. The rats were administered the chemi...

cidyl Values after Ingestion of Phenazopyridine Hydrochloride

taken through this procedure for Placidyl (1). Curve A shows the scan of the chromogen formed when a urine sample, collected from a person who about 3 h before had ingested one 200mg Pyridium tablet, was diluted fivefold and taken through the assay. Curve B is a similar scan of the chromogen formed when a solution containing 2 mg/dl of Placidyl was taken through the same procedure. These spectr...

Methemoglobinemia from Prolonged Therapeutic Use of Phenazopyridine

Background: Phenazopyridine is often prescribed for patients suffering from urinary tract infections as its local analgesic properties can provide immediate symptomatic improvement. It is classically taken for two days while awaiting antibiotic effect. It is available without a prescription in the United States under the trade names: Azo Urinary Pain Relief, Uricalm, and Uristat. Common adverse...

Phenazopyridine-sulfonamide combination antibacterial therapy in mice.

Phenazopyridine, at its maximum tolerated dose, did not affect the effectiveness of sulfonamides against uropathogenic bacterial species in mice.